Intraepithelial carcinoma (Bowen disease) - Intraepithelial Carcinoma (Lefu La Bowen)
☆ Liphethong tsa 2022 Stiftung Warentest tse tsoang Jeremane, khotsofalo ea bareki ka ModelDerm e ne e le tlase hanyane ho feta lipuisano tse lefelloang tsa telemedicine.
Boemo bo tlwaelehileng ― Intraepithelial Carcinoma (Lefu La Bowen) (Intraepithelial carcinoma (Bowen disease)) e ka nna ya hlahlojwa hampe e le eczema e tšoarellang nako e telele, e sa hlohloneng.
References
Bowen's disease (BD) ke mofuta oa mofetše oa letlalo o qalang karolong e ka ntle ea letlalo (epidermis) . E atile haholo ho Caucasus mme hangata e hlaha libakeng tse hlasetsoeng ke letsatsi, empa e ka hlaha le libakeng tse ling. BD hangata e hlaha e le leqeba le le leng. Hangata BD e nkoa e le letšoao la temoso pele ho hlaha mofuta o tebileng haholoanyane oa kankere ea letlalo. Ho hlahloba BD, hangata lingaka li itšetlehile ka ho hlahloba lisampole tsa lisele tlas'a microscope (biopsy) .
Bowen's disease (BD) is an in-situ squamous cell carcinoma of epidermis. The etiology of BD is multifactorial with high incidence among Caucasians. BD is common in photo-exposed areas of skin, but other sites can also be involved. Lesions are usually solitary. The morphology of BD differs based on age of the lesion, site of origin, and the degree of keratinization. BD is considered as the lull before the storm, which precedes an overt squamous cell carcinoma. Histopathology is the gold standard diagnostic modality to confirm the diagnosis.
Bowen's disease (BD) is an in-situ squamous cell carcinoma of epidermis. The etiology of BD is multifactorial with high incidence among Caucasians. BD is common in photo-exposed areas of skin, but other sites can also be involved. Lesions are usually solitary. The morphology of BD differs based on age of the lesion, site of origin, and the degree of keratinization. BD is considered as the lull before the storm, which precedes an overt squamous cell carcinoma. Histopathology is the gold standard diagnostic modality to confirm the diagnosis.
Bowen's disease haholo-holo e ama batho ba basoeu ba lilemo tse fetang 60. Lintlha tse ka sehloohong tsa kotsi li kenyelletsa ho ba letsatsing ka nako e telele, ho fokola ha sesole sa 'mele, ho pepesehela arsenic, le tšoaetso ea HPV ea letlalo. Mefuta ea HPV ea 16, 18, 34, le 48 e amahanngoa le lefu la Bowen libakeng tsa thobalano. Ho kenya letsoho ha HPV maemong ao e seng litho tsa botona le botšehali ha hoa hlaka.
Bowen disease is most commonly found in white patients over 60 years old. Other risk factors include chronic sun exposure, immunosuppression, arsenic exposure and cutaneous human papillomavirus (HPV) infection. HPV types 16, 18, 34 and 48 cause Bowen disease at genital sites; the role of HPV in nongenital cases of Bowen disease is less well defined. HPV types 2, 16, 34 and 35 have been rarely identified within nongenital lesions.
Bowen disease is most commonly found in white patients over 60 years old. Other risk factors include chronic sun exposure, immunosuppression, arsenic exposure and cutaneous human papillomavirus (HPV) infection. HPV types 16, 18, 34 and 48 cause Bowen disease at genital sites; the role of HPV in nongenital cases of Bowen disease is less well defined. HPV types 2, 16, 34 and 35 have been rarely identified within nongenital lesions.
Hangata e hlaha e le erythematous, scaly kapa crusty sebakeng sefe kapa sefe 'meleng. Sebaka se tloaelehileng haholo ke maoto a tlaase.
E ka phekoleha ka mekhoa e fapaneng ea kalafo e kang cryotherapy, curettage, cautery, photodynamic therapy, kapa excision ea lesion.
○ Tlhahlobo le Kalafo
#Dermoscopy
#Skin biopsy
#Mohs surgery
#Photodynamic therapy