Intraepithelial carcinoma (Bowen disease) - Intraepithelial Carcinoma (Lefu La Bowen)https://en.wikipedia.org/wiki/Squamous_cell_skin_cancer
Intraepithelial Carcinoma (Lefu La Bowen) (Intraepithelial carcinoma (Bowen disease)) e bontša lisele tsa squamous tse sa tloaelehang li ata ka har'a botenya bohle ba epidermis. Hlahala eohle e koalehile ka har'a epidermis, ’me ha e kene ka har'a letlalo. Lefu lena ka botekgeniki le hlalosoa e le mofetše, empa ha le tšoane le mofetše o tloaelehileng (ke hore ke mofetše o nang le ponelopele e ntle).

Hangata e hlaha e le erythematous, scaly kapa crusty sebakeng sefe le sefe ’meleng. Sebaka se tloaelehileng haholo ke maoto a tlaase.

E ka phekoleha ka mekhoa e fapaneng ea kalafo e kang cryotherapy, curettage, cautery, photodynamic therapy, kapa excision ea lesion.

Tlhahlobo le Kalafo
#Dermoscopy
#Skin biopsy
#Mohs surgery
#Photodynamic therapy
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  • Boemo bo tlwaelehileng — Intraepithelial Carcinoma (Lefu La Bowen) (Intraepithelial carcinoma (Bowen disease)) e ka hlahisoa ka hampe e le eczema e tšoarellang nako e telele, e sa hlohloneng.
  • Cutaneous horn — Ha e tšoane le li-warts; e hlaha e le nodule e thata, ’me ho hlokahala ho etsa biopsy ho netefatsa hore ha e le lefu le kotsi.
  • Haeba leqeba le tšoarella nako e telele, ho lokela ho nahana ka kankere ea letlalo.
  • Intraepithelial Carcinoma (Lefu la Bowen) (Intraepithelial carcinoma (Bowen disease)) — mofuta o tloaelehileng
  • Tabeng ena, Irritated seborrheic keratosise ka boela e nkoa e le tlhahlobo e ka bang teng ea phapang.
  • Hangata e nkoa e le phoso ea ho kula (mohlala, nummular eczema).
  • Intraepithelial Carcinoma (Lefu La Bowen) (Intraepithelial carcinoma (Bowen disease)) — Nyeoe e tloaelehileng.
  • Ntho e 'ngoe e tloaelehileng e fana ka likarolo tse tšoanang tsa morphology ho maemo a ho kula.
References Bowen's Disease 35287414 
NIH
Bowen's disease (BD) ke mofuta oa mofetše oa letlalo o qalang karolong e ka ntle ea letlalo (epidermis). E atile haholo ho Caucasus, ’me hangata e hlaha libakeng tse hlasetsoeng ke letsatsi, empa e ka hlaha le libakeng tse ling. BD hangata e hlaha e le leqeba le le leng. Hangata, BD e nkoa e le letšoao la temoso pele ho hlaha mofuta o tebileng haholoanyane oa kankere ea letlalo. Ho hlahloba BD, lingaka hangata li itšetlehile ka ho hlahloba lisampole tsa lisele tlas'a microscope (biopsy).
Bowen's disease (BD) is an in-situ squamous cell carcinoma of epidermis. The etiology of BD is multifactorial with high incidence among Caucasians. BD is common in photo-exposed areas of skin, but other sites can also be involved. Lesions are usually solitary. The morphology of BD differs based on age of the lesion, site of origin, and the degree of keratinization. BD is considered as the lull before the storm, which precedes an overt squamous cell carcinoma. Histopathology is the gold standard diagnostic modality to confirm the diagnosis.
 Bowen disease - Case reports 17001052 
NIH
Bowen's disease haholo-holo e ama batho ba basoeu ba fetang lilemo le 60. Lintlha tsa kotsi tse ka sehloohong li kenyelletsa ho ba le letsatsi le letelele, ho fokola ha sesole sa ‘mele, ho pepesehela arsenic, le tšoaetso ea HPV ea letlalo. Mefuta ea HPV 16, 18, 34, le 48 e amahanngoa le Bowen's disease libakeng tsa thobalano. Ho kenya letsoho ha HPV maemong ao e seng litho tsa botona le botšehali ha ho hlake.
Bowen disease is most commonly found in white patients over 60 years old. Other risk factors include chronic sun exposure, immunosuppression, arsenic exposure and cutaneous human papillomavirus (HPV) infection. HPV types 16, 18, 34 and 48 cause Bowen disease at genital sites; the role of HPV in nongenital cases of Bowen disease is less well defined. HPV types 2, 16, 34 and 35 have been rarely identified within nongenital lesions.